Supported from 2015 to 2021, this center created a strong and enduring collaborative partnership between researchers at the IIN and researchers at the U.S. Air Force Research Laboratory. Discovery-based research projects focused on the development of bioprogrammable nanomaterials to meet both military and civilian needs.
Sixteen research projects are described below, organized in the three thrust groups: Materials & Methods Development Thrust Group, the Functional Substrates Thrust Group, and the Advanced Biosensing Thrust Group.
Collectively, the C-ABN search program brought together an outstanding interdisciplinary team of academic researchers who, with their industrial and governmental partners, collectively focused on developing high-performance, functional materials from novel nanoscale building blocks utilizing the inherent chemical and biological recognition abilities of biomolecules.
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Thrust 1
Materials & Methods Development
Projects
- Stimulating Attention and Creative Problem Solving (Beeman/McKinley)
- Statics and Dynamics of Soft/Biological Structures and Hybrid Soft-Hard Assemblies (Dravid/Drummy)
- Design and Synthesis of Functional Synthetic Biomaterials (Jewett/Dennis)
- Synthetic, Bioprogrammable Lipid and Lipoprotein Particles for Phospholipid and Cholesterol Metabolism (Thaxton/Schatz/Hussain/Pachter)
- Printable and Flexible Bio-Integrated Electronic Inks (Hersam/Tabor/Maruyama)
- Protein Spherical Nucleic Acids for Enhanced Neuronal Stress Response (Mirkin/Jankford)
Thrust 2
Functional Substrates
Projects
- ProjScreening Nanotube Catalysts Through Scanning Probe Block Copolymer Lithography (Mirkin/Maruyama)
- Optical Metasurfaces by Evolutionary Design (Odom/Urbas)
- Using SAMDI Mass Spectrometry to Detect Analytes in Sweat and Saliva (Mrksich/Kim/Benavides/Martin)
- Programmable Migration of Nanoparticles on Surfaces Presenting Continuous Gradients of Biomolecules (Lee/Vaia)
- Bio-Supramolecular Scaffolds for Templated Assembly of Cathodes in Wearable Energy Storage (Stupp/Naik/Mirau/Durstock)
Thrust 3
Advanced Biosensing
Projects
- Programmable Molecular Magnetic Nanomaterials as MRI pH Sensors (Harris/Mirau/Goodson)
- Rapid Quantification of Salivary Cortisol through NanoFlares (Mirkin/Kelley-Loughnane/Chavez/Mirau)
- Monitoring and Moderating Stress Severity (Redei/Jankford)
- SERS Detection of Performance Targets (Schatz/Naik)
- Bioprogrammable Plasmonic Sensors for Human Performance Biomarkers (Van Duyne/Pachter/Chavez)
- Advancing Biosensor Development through Screening and Structural Characterization of RNA Regulation (Jewett/Lucks/Harbaugh/Kelley-Loughnane)